Extracorporeal Circulation Causes Release of Neutrophil Gelatinase-Associated Lipocalin (NGAL)

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Extracorporeal circulation causes release of neutrophil gelatinase-associated lipocalin (NGAL).

Extracorporeal circulation (ECC) used during cardiac surgery causes activation of several inflammatory systems. These events are not fully understood but are responsible for complications during the immediate postoperative period. Neutrophil gelatinase-associated lipocalin (NGAL), a member of the expanding lipocalin family, has recently been described as an inflammatory protein. In this study, ...

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Cancer remains one of the major cause of death in the Western world. Although, it has been demonstrated that new therapies can improve the outcome of cancer patients, still many patients relapse after treatment. Therefore, there is a need to identify novel factors involved in cancer development and/or progression. Recently, neutrophil gelatinase-associated lipocalin (NGAL) has been suggested as...

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Neutrophil gelatinase associated lipocalin (NGAL) in early detection of nephropathy in type 2 diabetic Iraqi patients

Background: Diabetic nephropathy is a common complication of diabetes mellitus type2. The neutrophil gelatinase Associated lippocallin (NGAL) is an ubiquitous protein consist of 178 amino acid. NGAL can be identified in plasma and urine starting 24 hours after a kidney injury resulting changes in glomerular filtration and tubular reabsorption and with increased secretion in tubular epithelial c...

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Neutrophil Gelatinase-Associated Lipocalin Levels During Pneumoperitoneum

BACKGROUND AND OBJECTIVES A temporary deterioration in renal function during pneumoperitoneum has been reported, but the extent is not known. A new marker for the early detection of renal injury, neutrophil gelatinase-associated lipocalin (NGAL), has been shown to increase in various conditions that affect renal function. This study was conducted to explore detrimental effects of pneumoperitone...

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Dual action of neutrophil gelatinase-associated lipocalin.

Neutrophil gelatinase-associated lipocalin (NGAL) is expressed and secreted by immune cells, hepatocytes, and renal tubular cells in various pathologic states. NGAL exerts bacteriostatic effects, which are explained by its ability to capture and deplete siderophores, small iron-binding molecules that are synthesized by certain bacteria as a means of iron acquisition. Consistently, NGAL deficien...

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ژورنال

عنوان ژورنال: Mediators of Inflammation

سال: 1999

ISSN: 0962-9351,1466-1861

DOI: 10.1080/09629359990504